Here are three things to watch on President Donald Trump's foreign trip.
This will be his "debut" trip, where he'll have to manage a politically complex itinerary, which will test his - already proven - diplomatic inexperience.
"It's nearly always true that when a president goes on a big foreign trip, especially one that has some important summits. that dominates the news and knocks most other stuff out", said Republican strategist Charlie Black.
Mr Trump has tried to put investigations into his campaign and his first four months in office behind him. US allies have been rattled by his warnings about pulling back from the world.
His travel ban orders are, however, stuck in the U.S. courts.
"Speeches would normally be worked on for four to six weeks in advance, but this is an understaffed White House that has been focused on a fusillade of bad news".
Ivanka converted to Judaism when she married Jared Kushner.
Still, Trump hasn't been eager to seize the opportunity.
But this experience could not be so disastrous if, despite the unpredictability of the President's character, his management could be shaped by an worldwide policy that expects of him much more than a good dealer.
He tweeted on Friday morning: "Getting ready for my big foreign trip".
Each stop comes with high stakes.
U.S. President Donald Trump's and Saudi Arabia's King's Salman bin Abdulaziz Al Saud's photos are seen with flags of both countries on an airport road as part of celebrations to welcome United States President Donald Trump, in Riyadh, Saudi Arabia on May 19.
"Throughout the summit, he will meet bilaterally with leaders, including the Italian Prime Minister Paolo Gentiloni". Despite a flourishing global business, Trump rarely leaves the USA and usually stays at his own properties when traveling, where workers reportedly know how he likes his food served and even what temperature to keep his room.
"We have to stop radical Islamic terrorism", he added. "And he will visit the Church of the Holy Sepulcher and say a prayer at the Western Wall", McMaster said. US policy holds that ownership of the holiest site where Jews can pray, as with the rest of Jerusalem, is subject to Israeli-Palestinian negotiation.
The avalanche of revelations in the run-up to his departure have eroded Trump's standing at home - where the parallels with Richard Nixon's ill-fated presidency are now being openly drawn.
When Cavuto asked what Trump would do if they refused, he assured him, "They will". Trump will likely discuss with his Arab interlocutors the shaping of an inclusive defense coalition, possibly an "Arab NATO", to address the region's security concerns. He recently has shifted to reassure wary allies that he remains committed to the pact.
"The speech is an incredibly risky move for the entire relationship", says James Zogby, President of the Arab American Institute". "And their - the goodness of people of all faiths will prevail over this evil".
In contrast to this wide spread, the interests of his real estate mogul son-in-law - who has been tasked with devising a Middle East peace plan - are quite concentrated. Though Pope Francis has said he'd "never make a judgment about a person without hearing him out", others on the continent have sharply criticized Trump. The Democratic lawmaker included on the list references to Trump's policies on climate change and immigration.
Trump will meet members of the North Atlantic alliance in Brussels, before heading on to a G7 summit in Taormina, a picturesque Sicilian town overlooking the Mediterranean.